Center for In Vivo Metabolism UTSW
Craig R. Malloy, MD

AIRC Medical Director

Personal Statment

Our understanding of metabolic pathways continues to evolve with the acquisition of information from metabolomics, proteomics, and transcriptomics. There is intense interest in understanding and modifying intermediary metabolism in cancer, diabetes and cardiovascular disease, but a major challenge is actually measuring fluxes in metabolic networks in vivo. Dr. Malloy has a long-standing interest in tracer-based analysis of metabolic pathways with translation to clinical applications. Although much of his effort is directed to 13C and 2H NMR spectroscopy, other complementary methods such as mass spectrometry, MR imaging and radiotracers provide valuable measurements. He serves as overall PI for the National Center for In Vivo Metabolism and point of contact for the External Advisory Committee. Along with Dr. Charlie Khemtong, he is the point of contact for scientific questions.

Members of the National Center for In Vivo Metabolism