tcaWEB is an online tool that allows the user to select a 13C isotopomer patterns of glucose or pyruvate and see the labelling results for major downstream metabolites:
- tcaWEB_Glucose allows the effects of 13C labels of glucose through glycolysis to pyruvate and even into the TCA cycle.
- tcaWEB_Pyruvate allows direct labelling of pyruvate and gives further options to activate or deactivate PDH or PC pathways into the TCA cycle.
Release Notes
| Date | Version | Comments |
|---|---|---|
| 03/22/2019 | 2.1 | Minor UI fixes. |
| 03/07/2019 | 2.0 | Introduced pyruvate as starting metabolite with buttons to enable PC and PDH pathways. Split into tcaWEB_Glucose & tcaWEB_Pyruvate for easier future development. |
| 12/17/2018 | 1.3 | Added additional TCA metabolites as output (turn 1 only). |
| 12/13/2018 | 1.2 | Major update of background graphics perfomance and button redesign. |
| 12/10/2018 | 1.1 | Added CO2 output from PDH. |
| 12/05/2018 | 1.0.1 | Fixed label identifiers for Acetyl-CoA. |
| 11/27/2018 | 1.0 | First stable release. Basic functionality working and simple GUI present. |
For any feedback, bugs or problems with you are experiences with tcaWEB please contact Alexander Funk.