Center for In Vivo Metabolism UTSW

The National Center of In Vivo Metabolism has been active since 1987 and has published numerous papers. Below we have an updated list of publications from not only faculty and staff of the Center, but also from collaborations using the Center's resources.
A full list is also available on the NIH profile of the Center grant.

Effects of glassing matrix deuteration on the relaxation properties of hyperpolarized 13C spins and free radical electrons at cryogenic temperatures.
Parish C, Niedbalski P, Wang Q, Khashami F, Hayati Z, Liu M, Song L, Lumata L, J Chem Phys. 2019 Jun 21;150(23):234307

A responsive MRI contrast agent for detection of excess copper(II) in the liver in vivo
Paranawithana NN, Martins AF, Clavijo Jordan V, Zhao P, Chirayil S, Meloni G, Sherry AD, J.Am.Chem.Soc, 2019, in Press.

Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver
Fletcher JA, Deja S, Satapati S, Fu X, Burgess SC, Browning JD, JCI insight, 2019, in Press.

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver
Cappel DA, Deja S, Duarte JAG, Kucejova B, Inigo M, Fletcher JA, Fu X, Berglund E, Liu T, Elmquist JK, Hammer S, Mishra P, Browning JD, Burgess SC, Cell Metabolism, in Press.

Targeted Determination of Tissue Energy Status by LC-MS/MS
Fu X, Deja S, Kucejova B, Duarte JAG, McDonald JG, Burgess SC, Anal. Chem., in Press.

Metabolism of hyperpolarized 13C‐acetoacetate to β‐hydroxybutyrate detects real‐time mitochondrial redox state and dysfunction in heart tissue
Chen W, Sharma G, Maptue NR, Malloy CR, Sherry AD, Khemtong C, NMR in Biomedicine, 2019, in Press.

Assessing the pentose phosphate pathway using [2, 3‐13C2]glucose
Lee MH, Malloy CR, Corbin IR, Jin ES, NMR in Biomedicine, 2019, in Press.

The effect of flow on blood oxygen level dependent (R2∗) MRI of orthotopic lung tumors
Zhou H, Belzile O, Zhang Z, Wagner J, Ahn C, Richardson JA, Saha D, Brekken RA, Mason RP, Magn Reson Med., 2019, in Press.

Effects of Deuteration on Transamination and Oxidation of Hyperpolarized 13C-Pyruvate in the Isolated Heart
Funk AM, Wen X, Hever T, Maptue NR, Khemtong C, Sherry AD, Malloy CR, J Magn Reson, 2019, 301, 102-108.

Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency.
Jakkamsetti V, Marin-Valencia I, Ma Q, Good LB, Terrill T, Rajasekaran K, Pichumani K, Khemtong C, Hooshyar MA, Sundarrajan C, Patel MS, Bachoo RM, Malloy CR, Pascual JM, Sci Transl Med, 2019, 11 (480), eaan0457.

Modular 31P wideband inversion transfer for integrative analysis of adenosine triphosphate metabolism, T1 relaxation and molecular dynamics in skeletal muscle at 7T
Ren J, Sherry AD, Malloy CR, Magn Reson Med, 2019, in Press.

Multimodality Hyperpolarized C-13 MRS/PET/Multiparametric MR Imaging for Detection and Image-Guided Biopsy of Prostate Cancer: First Experience in a Canine Prostate Cancer Model.
Bachawal SV, Park JM, Valluru KS, Loft MD, Felt SA, Vilches-Moure JG, Saenz YF, Daniel B, Iagaru A, Sonn G, Cheng Z, Spielman DM, Willmann JK., Mol Imaging Biol. 2019, in Press.

In vivo assessment of increased oxidation of branched-chain amino acids in glioblastoma
Suh EH, Hackett EP, Wynn RM, Chuang DT, Luo W, Sherry AD, Park JM, Scientific Reports, 2019, 9(1), 340

Novel compounds that specifically bind and modulate MscL: insights into channel gating mechanisms
Wray R, Iscla I, Kovacs Z, Wang J, Blount P., FASEB J. 2019, 33(3), 3180-3189.

tcaSIM: A Simulation Program for Optimal Design of 13C Tracer Experiments for Analysis of Metabolic Flux by NMR and Mass Spectroscopy
Alger JR, Sherry AD, Malloy CR, Curr Metabolomics, 2018, 6(3) , 176-187.

Imaging insulin secretion from the mouse pancreas by MRI is improved by use of a zinc-responsive MRI sensor with lower affinity for Zn2+ ions
Martins AF, Clavijo Jordan V, Bochner F, Chirayil S, Paranawithana N, Zhang S, LO ST, Wen X, Zhao P, Neeman M, Sherry AD, JACS, 2018, in Press.

Probing carbohydrate metabolism using hyperpolarized 13C-labeled molecules
Singh J, Suh EH, Sharma G, Khemtong C, Sherry AD, Kovacs Z, NMR in Biomedicine, 2018, in Press.

Engineering a pH-Sensitive Liposomal MRI Agent by Modification of a Bacterial Channel
Yang LM, Zheng H, Ratnakar JS, Adebesin BY, Do QN, Kovacs Z, Blount P, Small. 2018, 14(19), 1704256

Esterase-catalyzed production of hyperpolarized 13C-enriched carbon dioxide in tissues for measuring pH
Maptue NR, Jiang W, Harrison C, Funk AM, Sharma G, Malloy CR, Sherry AD, Khemtong C, ACS Sens., 2018, 3(11),2232-2236.

Dynamic nuclear polarization of carbonyl and methyl 13C spins of acetate using 4-oxo-TEMPO free radical
Parish C, Niedbalski P, Kiswandhi A, Lumata L, J Chem Phys. 2018 , 149(5), 054302.

Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo
Courtney KD, Bezwada D, Mashimo T, Pichumani K, Vemireddy V, Funk AM, Wimberly J, McNeil SS, Kapur P, Lotan Y, Margulis V, Cadeddu JA, Pedrosa I, DeBerardinis RJ, Malloy CR, Bachoo RM, Maher EA, Cell Metab, 2018, 8, 1-8.

Crystallographic Characterization and Non-Innocent Redox Activity of the Glycine Modified DOTA Scaffold and Its Impact on Eu-III Electrochemistry
Burnett ME, Adebesin B, Ratnakar SJ, Green KN, Eur. J. Inorg. Chem., 2018, 14, 1556-1562.

MR-CBCT image-guided system for radiotherapy of orthotopic rat prostate tumors.
Chiu TD, Arai TJ, Campbell I J, Jiang SB, Mason RP, Stojadinovic S, PLoS One. 2018 May 30;13(5):e0198065.

Fatty Liver Disrupts Glycerol Metabolism in Gluconeogenic and Lipogenic Pathways in Humans
Jin ES, Browning JD Murphy RE, Malloy CR, J Lipid Res, 2018, 59(9), 1658-1694.

Anti-prostate cancer activity of 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide copper complexes in vivo by bioluminescence imaging
Xie F, Cai H, Peng F, J Biol Inorg Chem. 2018, in Press.

An adjustable-length Dipole Using Forced-Current Excitation For 7T MR
Cui J, Dimitrov IE, Cheshkov S, Gu M, Malloy CR, Wright SM, IEEE Trans. Biomed. Eng., 65(10), 2259-2266.

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation
Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN, Cell Rep. 2018, 23(13), 3701-3709.

Improved Efficacy of Synthesizing *MIII-Labeled DOTA Complexes in Binary Mixtures of Water and Organic Solvents. A Combined Radio- and Physicochemical Study.
Pérez-Malo M, Szabó G, Eppard E, Vagner A, Brücher E, Tóth I, Maiocchi A, Suh EH, Kovács Z, Baranyai Z, Rösch F, Inorg Chem. 2018, 57(10), 6107-6117

Advances in gadolinium-based MRI contrast agent designs for monitoring biological processes in vivo
Lux J, Sherry AD, Curr Opin Chem Biol. 2018, 45, 121-130.

A Novel Inhibitor of Pyruvate Dehydrogenase Kinase Stimulates Myocardial Carbohydrate Oxidation in Diet-Induced Obesity
Wu C, Satapati S, Gui W, Wynn RM, Sharma G, Lou M, Qi X, Burgess SC, Malloy CR, Khemtong C, Sherry AD, Chuang D, Merritt ME, J Biol Chem, 2018, 293(25), 9604-9613.

Presaturation Power Adjusted Pulsed CEST: A Method to Increase Independence of Target CEST Signal
Kikuchi K, Ishimatsu K, Zhang S, Dimitrov E, Honda H, Sherry AD, Takahashi M, Contrast Media Mol Imaging. 2018, 2018, 3141789

Pentose Phosphate Pathway Activity Parallels Lipogenesis but Not Antioxidant Processes in Rat Liver.
Jin ES, Lee MH, Murphy RE, Malloy CR, Am J Physiol Endocrinol Metab., 314(6), E543-E551.

Unveiling a hidden 31P signal coresonating with extracellular inorganic phosphate by outer-volume-suppression and localized 31P MRS in the human brain at 7T
Ren J, Shang T, Sherry AD, Malloy CR, Magn Reson Med. 2018, 80(4), 1289-1297.

Rational design of [13C,D14]tert-butylbenzene as a scaffold structure for designing long-lived hyperpolarized 13C probes.
Imakura Y, Nonaka H, Takakusagi Y, Ichikawa K, Maptue N, Funk AM, Khemtong C, Sando S, Chem Asian J., 2018, 13(3):280-283.

Nitroxyl Modified Tobacco Mosaic Virus as a Metal-Free High-Relaxivity MRI and EPR Active Superoxide Sensor
Dharmarwardana M, Martins AF, Chen Z, Palacios P, Nowak CM, Welch RP, Li S, Luzuriaga MA, Bleris L, Pierce BS, Sherry AD, Gassensmith JJ, Mol Pharm. 2018, 15(8), 2973-2983

Enhanced Efficiency of 13C Dynamic Nuclear Polarization by Superparamagnetic Iron Oxide Nanoparticle Doping
Niedbalski P, Parish CR, Wang Q, Hayati Z, Song L, Cleveland ZI, Lumata L, J. Phys. Chem. C, 2017, 121 (35), 19505-19511.

Influence of 13C Isotopic Labeling Location on Dynamic Nuclear Polarization of Acetate
Niedbalski P, Parish C, KIswandhi A, Kovacz Z, Lumata L, J. Phys. Chem. A, 2017, 121 (17), pp 3227–3233

Gallium(III) chelates of mixed phosphonate-carboxylate triazamacrocyclic ligands relevant to nuclear medicine: Structural, stability and in vivo studies
Prata MIM, André JP, Kovács Z, Takács AI, Tircsó G, Tóth I, Geraldes CFGC, J Inorg Biochem. 2017 Dec;177:8-16.

Lanthanide DO3A‐Tropone Complexes: Efficient Dual MR/NIR Imaging Probes in Aqueous Medium (Front Cover)
Hashami Z, Martins AF, Funk AM, Clavijo Jordan V, Petoud S, Eliseeva SV, Kovacs Z, Eur. J. Inorg. Chem., 2017, 4965-4968.

Zinc as an Imaging Biomarker of Prostate Cancer
Lo S-T, Martins AF, Clavijo Jordan V, Sherry AD, Isr. J. Chem, 2017, S7, 854-861

Lanthanide-Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents.
Zhang L, Martins AF, Zhao P, Wu Y, Tircsó G, Sherry AD, Angew Chem Int Ed Engl. 2017 Dec 22;56(52):16626-16630

Electrochemical investigation of the Eu3+/2+ redox couple in complexes with variable numbers of glycinamide and acetate pendant arms.
Burnett ME, Adebesin B, Funk AM, Kovacs Z, Sherry AD, Ekanger LA, Allen MJ, Green KN, Ratnakar SJ, Eur J Inorg Chem. 2017 Nov 24;2017(43):5001-5005

Transition Metal Doping Reveals Link between Electron T1 Reduction and 13C Dynamic Nuclear Polarization Efficiency.
Niedbalski P, Parish C, Wang Q, Hayati Z, Song L, Martins AF, Sherry AD, Lumata L, J Phys Chem A. 2017 Dec 7;121(48):9221-9228

Enantiomeric Recognition of d- and l-Lactate by CEST with the Aid of a Paramagnetic Shift Reagent.
Zhang L, Martins AF, Zhao P, Tieu M, Esteban-Gómez D, McCandless GT, Platas-Iglesias C, Sherry AD, J Am Chem Soc. 2017 Dec 6;139(48):17431-17437

Cancer Metabolism and Tumor Heterogeneity: Imaging Perspectives Using MR Imaging and Spectroscopy.
Lin G, Keshari KR, Park JM, Contrast Media Mol Imaging. 2017 Oct 9;2017:6053879.

Measurement of 13C turnover into glutamate and glutamine pools in brain tumor patients.
Pichumani K, Mashimo T, Vemireddy V, Ijare OB, Mickey BE, Malloy CR, Marin-Valencia I, Baskin DS, Bachoo RM, Maher EA, FEBS Lett. 2017 Nov;591(21):3548-3554

The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.
Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME, J Biol Chem. 2017 Nov 3;292(44):18203-18216.

Lactate Metabolism in Human Lung Tumors.
Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ, Cell. 2017 Oct 5;171(2):358-371

Efficient 31 P band inversion transfer approach for measuring creatine kinase activity, ATP synthesis, and molecular dynamics in the human brain at 7 T.
Ren J, Sherry AD, Malloy CR, Magn Reson Med, 2017, 78(5):-1657-1666.

The rate of lactate production from glucose in hearts is not altered by per-deuteration of glucose.
Funk AM, Anderson BL, Wen X, Hever T, Khemtong C, Kovacs Z, Sherry AD, Malloy CR, J Magn Reson, 2017, 284, 86-93.

PKM2 activation sensitizes cancer cells to growth inhibition by 2-deoxy-D-glucose.
Tee SS, Park JM, Hurd RE, Brimacombe KR, Boxer MB, Massoud TF, Rutt BK, Spielman DM, Oncotarget. 2017 Jul 26;8(53):90959-90968

Protonation of carboxyl groups in EuDOTA-tetraamide complexes results in catalytic prototropic exchange and quenching of the CEST signal.
Zhang L, Evbuomwan OM, Tieu M, Zhao P, Martins AF, Sherry AD, Philos Trans A Math Phys Eng Sci. 2017 Nov 28;375(2107).

Imaging Extracellular Lactate In Vitro and In Vivo Using CEST MRI and a Paramagnetic Shift Reagent.
Zhang L, Martins AF, Mai Y, Zhao P, Funk AM, Clavijo Jordan MV, Zhang S, Chen W, Wu Y, Sherry AD, Chemistry. 2017 23(8):1752-1756.

Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized 13C magnetic resonance.
Mishkovsky M, Anderson B, Karlsson M, Lerche MH, Sherry AD, Gruetter R, Kovacs Z, Comment A, Sci Rep. 2017, 7(1):11719.

Measurement of glycine in healthy and tumorous brain by triple-refocusing MRS at 3 T in vivo.
Tiwari V, An Z, Ganji SK, Baxter J, Patel TR, Pan E, Mickey BE, Maher EA, Pinho MC, Choi C1, NMR Biomed. 2017 Sep;30(9)

Crosslinked shells for nano-assembled capsules: a new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities.
Farashishiko A, Plush SE, Maier KB, Dean Sherry A, Woods M, Chem Commun. 2017, 53(47):6355-6358.

In Vivo Assessment of Intracellular Redox State in Rat Liver Using Hyperpolarized [1-13C]Alanine
JM Park, C Khemtong, SC Liu, RE Hurd & DM Spielman. Magn Reson Med, 2017, 77(5), 1741-1748

A Comprehensive Analysis of Myocardial Substrate Preference Emphasizes the Need For a Synchronized Fluxomic/Metabolomic Research Design
M Ragavan, A Kirpich, X2 Fu, SC Burgess, LM McIntyre & ME Merritt, Am J Physiol Heart Circ Physiol, 2017, 312(6), H1215-H1223

Tumor physiological changes during hypofractionated stereotactic body radiation therapy assessed using multi-parametric magnetic resonance imaging.
Zhou H, Zhang Z, Denney R, Williams JS, Gerberich J, Stojadinovic S, Saha D, Shelton JM, Mason RP, Oncotarget. 2017, 8(23), 37464-37477

On-bead combinatorial synthesis and imaging of europium(III)-based paraCEST agents aids in identification of chemical features that enhance CEST sensitivity
J Singh, V Rustagi, S Zhang, AD Sherry & DG Udugamasooriya DG, Magn Reson Chem, 2017, 55(8), 747-753

Hyperpolarized δ-[1- 13C]gluconolactone as a probe of the pentose phosphate pathway
KX Moreno, CE Harrison, ME Merritt, Z Kovacs, CR Malloy & AD Sherry, NMR Biomed. 2017 Jun;30(6)

Intramyocellular lipid excess in the mitochondrial disorder MELAS: MRS determination at 7T.
Neurol Genet., Golla S, Ren J, Malloy CR, Pascual JM., 2017, 3(3), e160

Multiband Spectral-Spatial RF Excitation for Hyperpolarized [2-13C]Dihydroxyacetone 13C-MR Metabolism Studies
I Marco-Rius, P Cao, C von Morze, M Merritt, KX Moreno, GY Chang, MA Ohliger, D Pearce, J Kurhanewicz, PE Larson & DB Vigneron, Magn Reson Med, 2017, 77(4) 1419-1428

Hyperpolarized Sodium [1-13C]-Glycerate as a Probe for Assessing Glycolysis in Vivo
JM Park, M Wu, K Datta, S-C Liu, A Castillo, He Lough, DM Spielman & KL Billingsley, 2017, 139(19), 6629-6634.

Oxidation of [U-13C]glucose in the Human Brain at 7T under Steady State Conditions
S Cheshkov, IE Dimitrov, V Jakkamsetti, L Good, D Kelly, K Rajasekaran, RJ DeBerardinis, JM Pascual, AD Sherry & CR Malloy, Magn Reson Med, 2017, 78(6), 2065-20171

Real-time in vivo detection of H2O2 using hyperpolarized 13C-thiourea
A Wibowo, JM Park, Shie-C Liu, C Khosla & DM Spielman, ACS Chem. Biol, 2017, 12(7), 1737-1742

Band Inversion Amplifies 31P-31P Nuclear Overhauser Effects: Relaxation Mechanism and Dynamic Behavior of ATP in the Human Brain by 31P MRS at 7T
J Ren, AD Sherry & CR Malloy, Magn Reson Med, 2017, 77, 1409-1418

Elucidating the structural organization of a novel low-density lipoprotein nanoparticle reconstituted with docosahexaenoic acid.
Mulik RS, Zheng H, Pichumani K, Ratnakar J, Jiang QX, Corbin IR, Chem Phys Lipids. 2017 Apr;204:65-75

Influence of Dy3+ and Tb3+ doping on 13C dynamic nuclear polarization
P Niedbalski, C Parish, A Kiswandhi, L Fidelino, C Khemtong, Z Hayati, L Song, A Martins, AD Sherry & L Lumata, J Chem Phy, 2017, 7, 146, 014303.

Automated modification and fusion of voxel models to construct body phantoms with heterogeneous breast tissue: Application to MRI simulations.
Rispoli JV, Wright SM, Malloy CR, McDougall MP, J Biomed Graph Comput, 2017, 7(1),1-7

Effects of visceral adiposity on glycerol pathways in gluconeogenesis
IJ Neeland, C Hughes, CR Ayers, CR Malloy & ES Jin, Metabolism,2017, 67, 80-89

Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13C]dihydroxyacetone.
Marco-Rius I, von Morze C, Sriram R, Cao P, Chang GY, Milshteyn E, Bok RA, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB, Merritt M, Magn Reson Med. 2017, 77(1), 65-73

The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized 89 Y Complexes and Their Solution Structures.
Xing Y, Jindal AK, Regueiro-Figueroa M, Le Fur M, Kervarec N, Zhao P, Kovacs Z, Valencia L, Pérez-Lourido P, Tripier R, Esteban-Gómez D, Platas-Iglesias C, Sherry AD, Chemistry. 2016, 22(46), 16657-16667

Oxidative Conversion of a Europium(II)-Based T1 Agent to a Europium(III)-Based paraCEST Agent that can be Detected In Vivo by Magnetic Resonance Imaging
AM Funk, V Clavijo Jordan, AD Sherry, SJ Ratnakar & Z Kovacs, Angew Chem Int Ed Engl., 55, 5024-7 (2016).

Tumor radio-sensitivity assessment by means of volume data and magnetic resonance indices measured on prostate tumor bearing rats
A Belfatto, DA White, RP Mason, Z Zhang, S Stojadinovic, G Baroni & P Cerveri, Med Phys., 43,1275 (2016).

Unexpected Changes in the Population of Coordination Isomers for the Lanthanide Ion Complexes of DOTMA-Tetraglycinate
C Kumas, WS Fernando, P Zhao, M Regueiro-Figueroa, GE Kiefer, AF Martins, C Platas-Iglesias & AD Sherry AD, Inorg Chem., 2016, 55(18), 9297-305.

Novel application of complementary imaging techniques to examine in vivo glucose metabolism in the kidney.
Hato T, Friedman AN, Mang H, Plotkin Z, Dube S, Hutchins GD, Territo PR, McCarthy BP, Riley AA, Pichumani K, Malloy CR, Harris RA, Dagher PC, Sutton TA, Am J Physiol Renal Physiol. 2016, 310(8), F717-F725

Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents
CM Walker, M Merritt, JX Wang & JA Bankson , J Vis Exp., 2016, 110, e53607.

Zinc-sensitive MRI contrast agent detects differential release of Zn(II) ions from the healthy vs. malignant mouse prostate
MV Clavijo Jordan, ST Lo, S Chen, C Preihs, S Chirayil, S Zhang, P Kapur, WH Li, LM De Leon-Rodriguez, AJ Lubag, NM Rofsky & AD Sherry AD, Proc Natl Acad Sci U S A, 113, E5464-71 (2016).

Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma
C Changho, JM Raisanen, SK Ganji, S Zhang, SS McNeil, Z An, A Madan, K J Hatanpaa, V Vemireddy, CA Sheppard, D Oliver, KM Hulsey, V Tiwari, T Mashimo, J Battiste, S Barnett, CJ Madden, TR Patel, E Pan, CR Malloy, BE Mickey, RM Bachoo & EA Maher, J of Oncology, Vol 34, NUM33, Nov 20 (2016).

Investigation into the distinct subcellular effects of docosahexaenoic acid loaded low-density lipoprotein nanoparticles in normal and malignant murine liver cells.
Moss LR, Mulik RS, Van Treuren T, Kim SY, Corbin IR, Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2363-76

The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized 89Y Complexes and Their Solution Structures
Y Xing, AK Jindal, M Regueiro-Figueroa, M Le Fur, N Kervarec, P Zhao, Z Kovacs, L Valencia, P Pérez-Lourido, R Tripier, D Esteban-Gómez, C Platas-Iglesias & AD Sherry, Chemistry, 22, 16657-16667 (2016).

Hepatic Arterial Infusion of Low-Density Lipoprotein Docosahexaenoic Acid Nanoparticles Selectively Disrupts Redox Balance in Hepatoma Cells and Reduces Growth of Orthotopic Liver Tumors in Rats
X Wen, L Reynolds, RS Mulik, SY Kim, T Van Treuren, LH Nguyen, H Zhu, IR Corbin, Gastroenterology, 150, 488-98 (2016).

Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging
L Zhang, AA Habib, D Zhao,Oncotarget, 7, 38693-38706 (2016).

Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma
Choi C, Raisanen JM, Ganji SK, Zhang S, McNeil SS, An Z, Madan A, Hatanpaa KJ, Vemireddy V, Sheppard CA, Oliver D, Hulsey KM, Tiwari V, Mashimo T, Battiste J, Barnett S, Madden CJ, Patel TR, Pan E, Malloy CR, Mickey BE, Bachoo RM, Maher EA, J of Clinical Oncology, V 34, 33, Nov 20 (2016).s

Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13C]dihydroxyacetone
I Marco-Rius, C von Morze, R Sriram, P Cao, GY Chang, E Milshteyn, RA Bok, MA Ohliger, D Pearce, J Kurhanewicz, PE Larson, DB Vigneron & MM Merritt, Magn Reson Med, Nov 12 (2016). Issue online: 27 December 2016.

Integration of 13C Isotopomer Methods and Hyperpolarization Provides a Comprehensive Picture of Metabolism
AD Sherry & CR Malloy, eMagRes, 2016, 1, 885–900 (2016).

Biochemical Specificity in Human Cardiac Imaging by 13C Magnetic Resonance Imaging.
Malloy CR, Sherry AD. Circ Res. 2016 Nov 11;119(11):1146-1148.

Trap Design and Construction for High-Power Multinuclear Magnetic Resonance Experiments.
Rispoli JV, Dimitrov IE, Cheshkov S, Malloy C, Wright SM, McDougall MP. Concepts Magn Reson Part B Magn Reson Eng. 2016 Oct;46B(4):162-168.

Accelerated chemical shift imaging of hyperpolarized (13) C metabolites.
Wang JX, Merritt ME, Sherry AD, Malloy CR. Magn Reson Med. 2016 Oct;76(4):1033-8

Developing oxygen-enhanced magnetic resonance imaging as a prognostic biomarker of radiation response.
White DA1, Zhang Z, Li L, Gerberich J, Stojadinovic S, Peschke P, Mason RP. Cancer Lett. 2016 Sep 28;380(1):69-77

An Oral Load of [13C3]Glycerol and Blood NMR Analysis Detect Fatty Acid Esterification, Pentose Phosphate Pathway, and Glycerol Metabolism through the Tricarboxylic Acid Cycle in Human Liver.
Jin ES1, Sherry AD2, Malloy CR3. J Biol Chem. 2016 Sep 2;291(36):19031-41

A simple approach to evaluate the kinetic rate constant for ATP synthesis in resting human skeletal muscle at 7 T.
Ren J, Sherry AD, Malloy CR. NMR Biomed. 2016 Sep;29(9):1240-8.

Impact of Ho(3+)-doping on (13)C dynamic nuclear polarization using trityl OX063 free radical.
Kiswandhi A, Niedbalski P, Parish C, Kaur P, Martins A, Fidelino L, Khemtong C, Song L, Sherry AD, Lumata L. Phys Chem Chem Phys. 2016 Aug 21;18(31):21351-9.

A general chemical shift decomposition method for hyperpolarized (13) C metabolite magnetic resonance imaging.
Wang JX, Merritt ME, Sherry D, Malloy CR. Magn Reson Chem. 2016 Aug;54(8):665-73

Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity.
Kucejova B, Duarte J, Satapati S, Fu X, Ilkayeva O, Newgard CB, Brugarolas J, Burgess SC. Cell Rep. 2016 Jul 12;16(2):508-19.

pH imaging of mouse kidneys in vivo using a frequency-dependent paraCEST agent.
Wu Y, Zhang S, Soesbe TC, Yu J, Vinogradov E, Lenkinski RE, Sherry AD. Magn Reson Med. 2016 Jun;75(6):2432-41.

Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.
Taegtmeyer H, Young ME, Lopaschuk GD, Abel ED, Brunengraber H, Darley-Usmar V, Des Rosiers C, Gerszten R, Glatz JF, Griffin JL, Gropler RJ, Holzhuetter HG, Kizer JR, Lewandowski ED, Malloy CR, Neubauer S, Peterson LR, Portman MA, Recchia FA, Van Eyk JE, Wang TJ; Circ Res. 2016 May 13;118(10):1659-701

In vivo (1)H MRSI of glycine in brain tumors at 3T.
Ganji SK, Maher EA, Choi C, Magn Reson Med. 2016 Jan;75(1):52-62

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver.
Satapati S, Kucejova B, Duarte JA, Fletcher JA, Reynolds L, Sunny NE, He T, Nair LA, Livingston KA, Fu X, Merritt ME, Sherry AD, Malloy CR, Shelton JM, Lambert J, Parks EJ, Corbin I, Magnuson MA, Browning JD, Burgess SC. J Clin Invest. 2016 Apr 1;126(4):1605.

Metabolism of hyperpolarized [1-(13)C]pyruvate through alternate pathways in rat liver.
Jin ES, Moreno KX, Wang JX, Fidelino L, Merritt ME, Sherry AD, Malloy CR. NMR Biomed. 2016 Apr;29(4):466-74.

Metabolic Heterogeneity in Human Lung Tumors.
Hensley CT1, Faubert B, Yuan Q, Lev-Cohain N, Jin E, Kim J, Jiang L, Ko B, Skelton R, Loudat L, Wodzak M, Klimko C, McMillan E, Butt Y, Ni M, Oliver D, Torrealba J, Malloy CR, Kernstine K, Lenkinski RE, DeBerardinis RJ. Cell. 2016 Feb 11;164(4):681-94.

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation
J Cui, IE Dimitrov, S Cheshkov, M Gu, CR Malloy & SM Wright, Trans on Biomedical Engineering, 2017, 62(7), 1777-1783

Lactate Contributes to Glyceroneogenesis and Glyconeogenesis in Skeletal Muscle by Reversal of Pyruvate Kinase.
Jin ES, Sherry AD, Malloy CR, J Biol Chem. 2015 Dec 18;290(51):30486-97

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver.
Satapati S, Kucejova B, Duarte JA, Fletcher JA, Reynolds L, Sunny NE, He T, Nair LA, Livingston KA, Fu X, Merritt ME, Sherry AD, Malloy CR, Shelton JM, Lambert J, Parks EJ, Corbin I, Magnuson MA, Browning JD, Burgess SC.,J Clin Invest. 2015 Dec;125(12):4447-62

Amplification of the effects of magnetization exchange by (31) P band inversion for measuring adenosine triphosphate synthesis rates in human skeletal muscle.
Ren J, Sherry AD, Malloy CR, Magn Reson Med. 2015 Dec;74(6):1505-14.

Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors.
Bankson JA, Walker CM, Ramirez MS, Stefan W, Fuentes D, Merritt ME, Lee J, Sandulache VC, Chen Y, Phan L, Chou PC, Rao A, Yeung SC, Lee MH, Schellingerhout D, Conrad CA, Malloy C, Sherry AD, Lai SY, Hazle JD, Cancer Res. 2015 Nov 15;75(22):4708-17.

(31)P-MRS of healthy human brain: ATP synthesis, metabolite concentrations, pH, and T1 relaxation times.
Ren, Sherry AD, Malloy CR, NMR Biomed. 2015 Nov;28(11):1455-62

(68) Ga]-HP-DO3A-nitroimidazole: a promising agent for PET detection of tumor hypoxia.
Wu Y, Hao G, Ramezani S, Saha D, Zhao D, Sun X, Sherry AD, Contrast Media Mol Imaging. 2015 Nov-Dec;10(6):465-72

Production of hyperpolarized 13CO2 from [1-13C]pyruvate in perfused liver does reflect total anaplerosis but is not a reliable biomarker of glucose production.
Moreno KX, Moore CL, Burgess SC, Sherry AD, Malloy CR, Merritt ME, Metabolomics. 2015 Oct;11(5):1144-1156.

A roadmap for interpreting (13)C metabolite labeling patterns from cells.
Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM, Meuillet EJ, Munger J, Nöh K, Rabinowitz JD, Ralser M, Sauer U, Stephanopoulos G, St-Pierre J, Tennant DA, Wittmann C, Vander Heiden MG, Vazquez A, Vousden K, Young JD, Zamboni N, Fendt SM, Curr Opin Biotechnol. 2015 Aug;34:189-201

Basic MR relaxation mechanisms and contrast agent design.
De León-Rodríguez LM, Martins AF, Pinho MC, Rofsky NM, Sherry AD, J Magn Reson Imaging. 2015 Sep;42(3):545-65.

A pH-Responsive MRI Agent that Can Be Activated Beyond the Tissue Magnetization Transfer Window.
Wang X, Wu Y, Soesbe TC, Yu J, Zhao P, Kiefer GE, Sherry AD, Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8662-4

Development and performance of a 129-GHz dynamic nuclear polarizer in an ultra-wide bore superconducting magnet.
Lumata LL, Martin R, Jindal AK, Kovacs Z, Conradi MS, Merritt ME, MAGMA. 2015 Apr;28(2):195-205.

Molecular platform for design and synthesis of targeted dual-modality imaging probes.
Kumar A, Zhang S, Hao G, Hassan G, Ramezani S, Sagiyama K, Lo ST, Takahashi M, Sherry AD, Öz OK, Kovacs Z, Sun X, Bioconjug Chem. 2015 Mar 18;26(3):549-58.

Hyperpolarized 15N-pyridine derivatives as pH-sensitive MRI agents.
Jiang W, Lumata L, Chen W, Zhang S, Kovacs Z, Sherry AD, Khemtong C, Sci Rep. 2015 Mar 16;5:9104.

Hyperpolarized 13C NMR detects rapid drug-induced changes in cardiac metabolism.
Khemtong C, Carpenter NR, Lumata LL, Merritt ME, Moreno KX, Kovacs Z, Malloy CR, Sherry AD, Magn Reson Med. 2015 Aug;74(2):312-9.

Nuclear spin hyperpolarization of the solvent using signal amplification by reversible exchange (SABRE).
Moreno KX, Nasr K, Milne M, Sherry AD, Goux WJ, J Magn Reson. 2015 Aug;257:15-23.

Dynamic oxygen challenge evaluated by NMR T1 and T2*--insights into tumor oxygenation.
Zhao D, Pacheco-Torres J, Hallac RR, White D, Peschke P, Cerdán S, Mason RP, NMR Biomed. 2015 Aug;28(8):937-947.

Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas.
Pichumani K, Mashimo T, Baek HM, Ratnakar J, Mickey B, DeBerardinis RJ, Maher EA, Bachoo RM, Malloy CR, Kovacs Z, Anal Biochem. 2015 Jul 15;481:4-6

A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation.
Cui J, Bosshard JC, Rispoli JV, Dimitrov IE, Cheshkov S, McDougall MP, Malloy C, Wright SM. IEEE Trans Biomed Eng, 2015 Jul;62(7):1777-83.

Exchange kinetics by inversion transfer: integrated analysis of the phosphorus metabolite kinetic exchanges in resting human skeletal muscle at 7 T.
Ren J1, Yang B, Sherry AD, Malloy CR, Magn Reson Med. 2015 Apr;73(4):1359-69

Limitations of detection of anaplerosis and pyruvate cycling from metabolism of [1-(13)C] acetate.
Burgess SC, Merritt ME, Jones JG, Browning JD, Sherry AD, Malloy CR, Nat Med. 2015 Feb;21(2):108-9.

Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs.
Lumata L, Yang C, Ragavan M, Carpenter N, DeBerardinis RJ Merritt ME, Methods Enzymol. 2015;561:73-106.

Influence of liver triglycerides on suppression of glucose production by insulin in men.
Jin ES, Szuszkiewicz-Garcia M, Browning JD, Baxter JD, Abate N, Malloy CR, J Clin Endocrinol Metab. 2015 Jan;100(1):235-43.

The ratio of acetate-to-glucose oxidation in astrocytes from a single 13C NMR spectrum of cerebral cortex.
Marin-Valencia I, Hooshyar MA, Pichumani K, Sherry AD, Malloy CR, J Neurochem. 2015 Jan;132(1):99-109.

Real-time detection of hepatic gluconeogenic and glycogenolytic states using hyperpolarized [2-13C]dihydroxyacetone.
Moreno KX, Satapati S, DeBerardinis RJ, Burgess SC, Malloy CR, Merritt ME, J Biol Chem. 2014 Dec 26;289(52):35859-67

MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver.
Baskin KK, Grueter CE, Kusminski CM, Holland WL, Bookout AL, Satapati S, Kong YM, Burgess SC, Malloy CR, Scherer PE, Newgard CB, Bassel-Duby R, Olson EN, EMBO Mol Med. 2014 Dec;6(12):1610-21.

Interaction between the pentose phosphate pathway and gluconeogenesis from glycerol in the liver.
Jin ES, Sherry AD, Malloy CR, J Biol Chem. 2014 Nov 21;289(47):32593-603.

Quadrature transmit coil for breast imaging at 7 tesla using forced current excitation for improved homogeneity.
McDougall MP, Cheshkov S, Rispoli J, Malloy C, Dimitrov I, Wright SM, J Magn Reson Imaging. 2014 Nov;40(5):1165-73.

Propionate stimulates pyruvate oxidation in the presence of acetate.
Purmal C, Kucejova B, Sherry AD, Burgess SC, Malloy CR, Merritt ME, Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1134-41.

Simultaneous steady-state and dynamic 13C NMR can differentiate alternative routes of pyruvate metabolism in living cancer cells.
Yang C1, Harrison C, Jin ES, Chuang DT, Sherry AD, Malloy CR, Merritt ME, DeBerardinis RJ, J Biol Chem. 2014 Feb 28;289(9):6212-24.

Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.
Mashimo T, Pichumani K, Vemireddy V, Hatanpaa KJ, Singh DK, Sirasanagandla S, Nannepaga S, Piccirillo SG, Kovacs Z, Foong C, Huang Z, Barnett S, Mickey BE, DeBerardinis RJ, Tu BP, Maher EA, Bachoo RM, Cell. 2014 Dec 18;159(7):1603-14.

Hyperpolarized magnetic resonance as a sensitive detector of metabolic function.
Comment A, Merritt ME, Biochemistry. 2014 Dec 2;53(47):7333-57.

A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice.
Duarte JA, Carvalho F, Pearson M, Horton JD, Browning JD, Jones JG, Burgess SC, J Lipid Res. 2014 Dec;55(12):2541-53.

Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
Yang C, Ko B1, Hensley CT, Jiang L, Wasti AT, Kim J, Sudderth J, Calvaruso MA, Lumata L, Mitsche M, Rutter J, Merritt ME, DeBerardinis RJ, Mol Cell. 2014 Nov 6;56(3):414-24.

Metabolic characteristics of human hearts preserved for 12 hours by static storage, antegrade perfusion, or retrograde coronary sinus perfusion.
Cobert ML, Merritt ME, West LM, Ayers C, Jessen ME, Peltz M, J Thorac Cardiovasc Surg. 2014 Nov;148(5):2310-231

The presence of fast-exchanging proton species in aqueous solutions of paraCEST agents can impact rate constants measured for slower exchanging species when fitting CEST spectra to the Bloch equations.
Evbuomwan OM, Lee J, Woods M, Sherry AD, Inorg Chem. 2014 Oct 6;53(19):10012-4.

In vivo detection of citrate in brain tumors by 1H magnetic resonance spectroscopy at 3T.
Choi C, Ganji SK, Madan A, Hulsey KM, An Z, Zhang S, Pinho MC, DeBerardinis RJ, Bachoo RM, Maher EA, Magn Reson Med. 2014 Aug;72(2):316-23

Redox- and hypoxia-responsive MRI contrast agents.
Do QN, Ratnakar JS, Kovács Z, Sherry AD, ChemMedChem. 2014 Jun;9(6):1116-29.

In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.
Sagiyama K, Mashimo T, Togao O, Vemireddy V, Hatanpaa KJ, Maher EA, Mickey BE, Pan E, Sherry AD, Bachoo RM, Takahashi M, Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4542-7

Maximizing T2-exchange in Dy(3+)DOTA-(amide)X chelates: fine-tuning the water molecule exchange rate for enhanced T2 contrast in MRI.
Soesbe TC, Ratnakar SJ, Milne M, Zhang S, Do QN, Kovacs Z, Sherry AD, Magn Reson Med. 2014 Mar;71(3):1179-85

GdDO3NI, a nitroimidazole-based T1 MRI contrast agent for imaging tumor hypoxia in vivo.
Gulaka PK, Rojas-Quijano F, Kovacs Z, Mason RP, Sherry AD, Kodibagkar VD, J Biol Inorg Chem. 2014 Feb;19(2):271-9.

The stereochemistry of amide side chains containing carboxyl groups influences water exchange rates in EuDOTA-tetraamide complexes.
Mani T, Opina AC, Zhao P, Evbuomwan OM, Milburn N, Tircso G, Kumas C, Sherry AD, J Biol Inorg Chem. 2014 Feb;19(2):161-71

In vivo imaging of paraCEST agents using frequency labeled exchange transfer MRI.
Lin CY, Yadav NN, Ratnakar J, Sherry AD, van Zijl PC, Magn Reson Med. 2014 Jan;71(1):286-93

Reproducibility and absolute quantification of muscle glycogen in patients with glycogen storage disease by 13C NMR spectroscopy at 7 Tesla.
Heinicke K, Dimitrov IE, Romain N, Cheshkov S, Ren J, Malloy CR, Haller RG, PLoS One. 2014 Oct 8;9(10):e108706.

A 16-channel receive, forced current excitation dual-transmit coil for breast imaging at 7T.
By S, Rispoli JV, Cheshkov S, Dimitrov I, Cui J, Seiler S, Goudreau S, Malloy C, Wright SM, McDougall MP, PLoS One. 2014 Nov 24;9(11):e113969

A comparative study of short- and long-TE 1H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.
Choi C, Ganji S, Hulsey K, Madan A, Kovacs Z, Dimitrov I, Zhang S, Pichumani K, Mendelsohn D, Mickey B, Malloy C, Bachoo R, Deberardinis R, Maher E, NMR Biomed. 2013 Oct;26(10):1242-50.

Noninvasive monitoring of lactate dynamics in human forearm muscle after exhaustive exercise by (1)H-magnetic resonance spectroscopy at 7 tesla.
Ren J, Dean Sherry A, Malloy CR, Magn Reson Med. 2013 Sep;70(3):610-9.

Modeling of brain metabolism and pyruvate compartmentation using (13)C NMR in vivo: caution required.
Jeffrey FM, Marin-Valencia I, Good LB, Shestov AA, Henry PG, Pascual JM, Malloy CR, J Cereb Blood Flow Metab. 2013 Aug;33(8):1160-7.

Electron spin resonance studies of trityl OX063 at a concentration optimal for DNP.
Lumata L, Kovacs Z, Sherry AD, Malloy C, Hill S, van Tol J, Yu L, Song L, Merritt ME, Phys Chem Chem Phys. 2013 Jun 28;15(24):9800-7.

Metabolism of glycerol, glucose, and lactate in the citric acid cycle prior to incorporation into hepatic acylglycerols.
Jin ES, Sherry AD, Malloy CR, J Biol Chem. 2013 May 17;288(20):14488-96.

Dissolution DNP-NMR spectroscopy using galvinoxyl as a polarizing agent.
Lumata LL, Merritt ME, Malloy CR, Sherry AD, van Tol J, Song L, Kovacs Z, J Magn Reson. 2013 Feb;227:14-9.

Evidence for transaldolase activity in the isolated heart supplied with [U-13C3]glycerol.
Jin ES, Sherry AD, Malloy CR. J Biol Chem. 2013 Feb 1;288(5):2914-22.

Heptanoate as a neural fuel: energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain.
Marin-Valencia I, Good LB, Ma Q, Malloy CR, Pascual JM, J Cereb Blood Flow Metab. 2013 Feb;33(2):175-82.

Hepatic glucose production pathways after three days of a high-fat diet.
Jin ES, Beddow SA, Malloy CR, Samuel VT, Metabolism. 2013 Jan;62(1):152-62.

Dynamic monitoring of carnitine and acetylcarnitine in the trimethylamine signal after exercise in human skeletal muscle by 7T 1H-MRS.
Ren J, Lakoski S, Haller RG, Sherry AD, Malloy CR, Magn Reson Med. 2013 Jan;69(1):7-17.

Modulation of CEST images in vivo by T1 relaxation: a new approach in the design of responsive PARACEST agents.
Ratnakar SJ, Soesbe TC, Lumata LL, Do QN, Viswanathan S, Lin CY, Sherry AD, Kovacs Z, J Am Chem Soc. 2013 Oct 9;135(40):14904-7

Multi-chromatic pH-activatable 19F-MRI nanoprobes with binary ON/OFF pH transitions and chemical-shift barcodes.
Huang X, Huang G, Zhang S, Sagiyama K, Togao O, Ma X, Wang Y, Li Y, Soesbe TC, Sumer BD, Takahashi M, Sherry AD, Gao J, Angew Chem Int Ed Engl. 2013 Jul 29;52(31):8074-8.

A novel class of polymeric pH-responsive MRI CEST agents.
Zhang S, Zhou K, Huang G, Takahashi M, Sherry AD, Gao J,Chem Commun (Camb). 2013 Jul 21;49(57):6418-20

A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition.
Wan M, Leavens KF, Hunter RW, Koren S, von Wilamowitz-Moellendorff A, Lu M, Satapati S, Chu Q, Sakamoto K, Burgess SC, Birnbaum MJ, Cell Metab. 2013 Jul 2;18(1):99-105

PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis.
Méndez-Lucas A, Duarte JA, Sunny NE, Satapati S, He T, Fu X, Bermúdez J, Burgess SC, Perales JC, J Hepatol. 2013 Jul;59(1):105-13

Advantages of paramagnetic chemical exchange saturation transfer (CEST) complexes having slow to intermediate water exchange properties as responsive MRI agents.
Soesbe TC, Wu Y, Dean Sherry A, NMR Biomed. 2013 Jul;26(7):829-38.

A europium(III)-based PARACEST agent for sensing singlet oxygen by MRI.
Song B, Wu Y, Yu M, Zhao P, Zhou C, Kiefer GE, Sherry AD, Dalton Trans. 2013 Jun 14;42(22):8066-9.

Influence of deuteration in the glassing matrix on 13C dynamic nuclear polarization.
Lumata L, Merritt ME, Kovacs Z, Phys Chem Chem Phys. 2013 May 21;15(19):7032-5

The importance of water exchange rates in the design of responsive agents for MRI.
Sherry AD, Wu Y, Curr Opin Chem Biol. 2013 Apr;17(2):167-74

Weight-independent effects of roux-en-Y gastric bypass on glucose homeostasis via melanocortin-4 receptors in mice and humans.
Zechner JF, Mirshahi UL, Satapati S, Berglund ED, Rossi J, Scott MM, Still CD, Gerhard GS, Burgess SC, Mirshahi T, Aguirre V, Gastroenterology. 2013 Mar;144(3):580-590.e7

Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice.
Potthoff MJ, Potts A, He T, Duarte JA, Taussig R, Mangelsdorf DJ, Kliewer SA, Burgess SC, Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G371-80.

Cortical metabolism in pyruvate dehydrogenase deficiency revealed by ex vivo multiplet (13)C NMR of the adult mouse brain.
Marin-Valencia I, Good LB, Ma Q, Malloy CR, Patel MS, Pascual JM, Neurochem Int. 2012 Dec;61(7):1036-43.

Comparison of kinetic models for analysis of pyruvate-to-lactate exchange by hyperpolarized 13C NMR.
Harrison C, Yang C, Jindal A, DeBerardinis RJ, Hooshyar MA, Merritt M, Dean Sherry A, Malloy CR, NMR Biomed. 2012 Nov;25(11):1286-94.

Metabolism of [U-13C]glucose in human brain tumors in vivo.
Maher EA1, Marin-Valencia I, Bachoo RM, Mashimo T, Raisanen J, Hatanpaa KJ, Jindal A, Jeffrey FM, Choi C, Madden C, Mathews D, Pascual JM, Mickey BE, Malloy CR, DeBerardinis RJ, NMR Biomed. 2012 Nov;25(11):1234-44

Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.
Marin-Valencia I, Cho SK, Rakheja D, Hatanpaa KJ, Kapur P, Mashimo T, Jindal A, Vemireddy V, Good LB, Raisanen J, Sun X, Mickey B, Choi C, Takahashi M, Togao O, Pascual JM, Deberardinis RJ, Maher EA, Malloy CR, Bachoo RM, NMR Biomed. 2012 Oct;25(10):1177-86

Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.
Marin-Valencia I, Yang C, Mashimo T, Cho S, Baek H, Yang XL, Rajagopalan KN, Maddie M, Vemireddy V, Zhao Z, Cai L, Good L, Tu BP, Hatanpaa KJ, Mickey BE, Matés JM, Pascual JM, Maher EA, Malloy CR, Deberardinis RJ, Bachoo RM, Cell Metab. 2012 Jun 6;15(6):827-37.

Impact of Gd3+ on DNP of [1-13C]pyruvate doped with trityl OX063, BDPA, or 4-oxo-TEMPO.
Lumata L, Merritt ME, Malloy CR, Sherry AD, Kovacs Z, J Phys Chem A. 2012 May 31;116(21):5129-38

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Choi C, Ganji SK, DeBerardinis RJ, Hatanpaa KJ, Rakheja D, Kovacs Z, Yang XL, Mashimo T, Raisanen JM, Marin-Valencia I, Pascual JM, Madden CJ, Mickey BE, Malloy CR, Bachoo RM, Maher EA, Nat Med. 2012 Jan 26;18(4):624-9.

High-resolution detection of 13C multiplets from the conscious mouse brain by ex vivo NMR spectroscopy.
Marin-Valencia I, Good LB, Ma Q, Jeffrey FM, Malloy CR, Pascual JM, J Neurosci Methods. 2012 Jan 15;203(1):50-5

In vivo determination of human breast fat composition by 1H magnetic resonance spectroscopy at 7 T.
Dimitrov IE, Douglas D, Ren J, Smith NB, Webb AG, Sherry AD, Malloy CR, Magn Reson Med. 2012 Jan;67(1):20-6

SWIFT-CEST: a new MRI method to overcome T₂ shortening caused by PARACEST contrast agents.
Soesbe TC, Togao O, Takahashi M, Sherry AD, Magn Reson Med. 2012 Sep;68(3):816-21

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver.
Satapati S, Sunny NE, Kucejova B, Fu X, He TT, Méndez-Lucas A, Shelton JM, Perales JC, Browning JD, Burgess SC, J Lipid Res. 2012 Jun;53(6):1080-92.

Novel Fe3+-Based 1H MRI β-Galactosidase Reporter Molecules**
Yu JX, Gulaka PK, Liu L, Kodibagkar VD, Mason RP, Chempluschem. 2012 May 1;77(5):370-378.

Europium(III) DOTA-tetraamide complexes as redox-active MRI sensors.
Ratnakar SJ, Viswanathan S, Kovacs Z, Jindal AK, Green KN, Sherry AD, J Am Chem Soc. 2012 Apr 4;134(13):5798-800.

Using frequency-labeled exchange transfer to separate out conventional magnetization transfer effects from exchange transfer effects when detecting ParaCEST agents.
Lin CY, Yadav NN, Friedman JI, Ratnakar J, Sherry AD, van Zijl PC, Magn Reson Med. 2012 Apr;67(4):906-11.

Amphiphilic EuDOTA-tetraamide complexes form micelles with enhanced CEST sensitivity.
Evbuomwan OM, Kiefer G, Sherry AD, Eur J Inorg Chem. 2012 Apr 1;2012(12):2126-2134.

T2 measurement of J-coupled metabolites in the human brain at 3T.
Ganji SK, Banerjee A, Patel AM, Zhao YD, Dimitrov IE, Browning JD, Brown ES, Maher EA, Choi C, NMR Biomed. 2012 Apr;25(4):523-9

A second generation MRI contrast agent for imaging zinc ions in vivo.
De León-Rodríguez LM, Lubag AJ, López JA, Andreu-de-Riquer G, Alvarado-Monzón JC, Sherry AD, Medchemcomm. 2012 Apr 1;3(4):480-483.

Dual 19F/1H MR gene reporter molecules for in vivo detection of β-galactosidase.
Yu JX, Kodibagkar VD, Hallac RR, Liu L, Mason RP, Bioconjug Chem. 2012 Mar 21;23(3):596-603.

The effect of short-term fasting on liver and skeletal muscle lipid, glucose, and energy metabolism in healthy women and men.
Browning JD, Baxter J, Satapati S, Burgess SC, J Lipid Res. 2012 Mar;53(3):577-86.

Production and NMR characterization of hyperpolarized (107,109)Ag complexes.
Lumata L, Merritt ME, Hashami Z, Ratnakar SJ, Kovacs Z, Angew Chem Int Ed Engl. 2012 Jan 9;51(2):525-7

Nanoparticle-based PARACEST agents: the quenching effect of silica nanoparticles on the CEST signal from surface-conjugated chelates.
Evbuomwan OM, Merritt ME, Kiefer GE, Dean Sherry A, Contrast Media Mol Imaging. 2012 Jan-Feb;7(1):19-25.

The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy.
Lumata L, Merritt M, Khemtong C, Ratnakar SJ, van Tol J, Yu L, Song L, Kovacs Z, RSC Adv. 2012 Jan 1;2(33):12812-12817

Transfer of hyperpolarization from long T1 storage nuclei to short Tsub>1 neighbors using FLOPSY-8.
Moreno KX, Harrison C, Sherry AD, Malloy CR, Merritt ME, J Magn Reson. 2011 Dec;213(1):187-91.

Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance.
Merritt ME, Harrison C, Sherry AD, Malloy CR, Burgess SC, Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19084-9

Animal models of the human mind: is there anything like being autistic?
Pascual JM, Neurosci Lett. 2011 Nov 14;505(2):59-60.

Could 13C MRI assist clinical decision-making for patients with heart disease?
Malloy CR, Merritt ME, Sherry AD, NMR Biomed. 2011 Oct;24(8):973-9.

BDPA: an efficient polarizing agent for fast dissolution dynamic nuclear polarization NMR spectroscopy.
Lumata L, Ratnakar SJ, Jindal A, Merritt M, Comment A, Malloy C, Sherry AD, Kovacs Z, Chemistry. 2011 Sep 19;17(39):10825-7.

Measurement of glycine in the human brain in vivo by 1H-MRS at 3 T: application in brain tumors.
Choi C, Ganji SK, DeBerardinis RJ, Dimitrov IE, Pascual JM, Bachoo R, Mickey BE, Malloy CR, Maher EA, Magn Reson Med. 2011 Sep;66(3):609-18.

A lanthanide complex with dual biosensing properties: CEST (chemical exchange saturation transfer) and BIRDS (biosensor imaging of redundant deviation in shifts) with europium DOTA-tetraglycinate.
Coman D, Kiefer GE, Rothman DL, Sherry AD, Hyder F, NMR Biomed. 2011 Dec;24(10):1216-25

Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Mullen AR, Wheaton WW, Jin ES, Chen PH, Sullivan LB, Cheng T, Yang Y, Linehan WM, Chandel NS, DeBerardinis RJ, Nature. 2011 Nov 20;481(7381):385-8.

Noninvasive MRI of β-cell function using a Zn2+-responsive contrast agent.
Lubag AJ, De Leon-Rodriguez LM, Burgess SC, Sherry AD, Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18400-5.

The pH sensitivity of -NH exchange in LnDOTA-tetraamide complexes varies with amide substituent.
Opina AC, Wu Y, Zhao P, Kiefer G, Sherry AD, Contrast Media Mol Imaging. 2011 Nov-Dec;6(6):459-64.

Towards the rational design of MRI contrast agents: δ-substitution of lanthanide(III) NB-DOTA-tetraamide chelates influences but does not control coordination geometry.
Carney CE, Tran AD, Wang J, Schabel MC, Sherry AD, Woods M, Chemistry. 2011 Sep 5;17(37):10372-8

On-bead combinatorial synthesis and imaging of chemical exchange saturation transfer magnetic resonance imaging agents to identify factors that influence water exchange.
Napolitano R, Soesbe TC, De León-Rodríguez LM, Sherry AD, Udugamasooriya DG, J Am Chem Soc. 2011 Aug 24;133(33):13023-30.

Investigations into whole water, prototropic and amide proton exchange in lanthanide(III) DOTA-tetraamide chelates.
Woods M, Pasha A, Zhao P, Tircso G, Chowdhury S, Kiefer G, Woessner DE, Sherry AD, Dalton Trans. 2011 Jul 7;40(25):6759-64

FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway.
Potthoff MJ, Boney-Montoya J, Choi M, He T, Sunny NE, Satapati S, Suino-Powell K, Xu HE, Gerard RD, Finck BN, Burgess SC, Mangelsdorf DJ, Kliewer SA, Cell Metab. 2011 Jun 8;13(6):729-38

In vivo near-infrared spectroscopy and magnetic resonance imaging monitoring of tumor response to combretastatin A-4-phosphate correlated with therapeutic outcome.
Zhao D, Chang CH, Kim JG, Liu H, Mason RP, Int J Radiat Oncol Biol Phys. 2011 Jun 1;80(2):574-81

Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death.
Kucejova B, Sunny NE, Nguyen AD, Hallac R, Fu X, Peña-Llopis S, Mason RP, Deberardinis RJ, Xie XJ, Debose-Boyd R, Kodibagkar VD, Burgess SC, Brugarolas J, Oncogene. 2011 May 5;30(18):2147-60.

Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction.
Browning JD, Baker JA, Rogers T, Davis J, Satapati S, Burgess SC, Am J Clin Nutr. 2011 May;93(5):1048-52.

A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment.
Mason RP, Zhao D, Liu L, Trawick ML, Pinney KG, Integr Biol (Camb). 2011 Apr;3(4):375-87

Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice.
Doi S, Zou Y, Togao O, Pastor JV, John GB, Wang L, Shiizaki K, Gotschall R, Schiavi S, Yorioka N, Takahashi M, Boothman DA, Kuro-o M, J Biol Chem. 2011 Mar 11;286(10):8655-65

Europium(III) DOTA-derivatives having ketone donor pendant arms display dramatically slower water exchange.
Green KN, Viswanathan S, Rojas-Quijano FA, Kovacs Z, Sherry AD, Inorg Chem. 2011 Mar 7;50(5):1648-55

Strategies for labeling proteins with PARACEST agents.
Vasalatiy O, Zhao P, Woods M, Marconescu A, Castillo-Muzquiz A, Thorpe P, Kiefer GE, Sherry AD, Bioorg Med Chem. 2011 Feb 1;19(3):1106-14

TmDOTA-tetraglycinate encapsulated liposomes as pH-sensitive LipoCEST agents.
Opina AC, Ghaghada KB, Zhao P, Kiefer G, Annapragada A, Sherry AD, PLoS One. 2011;6(11):e27370.

Ventilation/perfusion imaging of the lung using ultra-short echo time (UTE) MRI in an animal model of pulmonary embolism.
Togao O, Ohno Y, Dimitrov I, Hsia CC, Takahashi M, J Magn Reson Imaging. 2011 Sep;34(3):539-46

DNP by thermal mixing under optimized conditions yields >60,000-fold enhancement of 89Y NMR signal.
Lumata L, Jindal AK, Merritt ME, Malloy CR, Sherry AD, Kovacs Z, J Am Chem Soc. 2011 Jun 8;133(22):8673-80.

The effect of 13C enrichment in the glassing matrix on dynamic nuclear polarization of [1-13C]pyruvate.
Lumata L, Kovacs Z, Malloy C, Sherry AD, Merritt M, Phys Med Biol. 2011 Mar 7;56(5):N85-92.

Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.
Kurhanewicz J, Vigneron DB, Brindle K, Chekmenev EY, Comment A, Cunningham CH, Deberardinis RJ, Green GG, Leach MO, Rajan SS, Rizi RR, Ross BD, Warren WS, Malloy CR, Neoplasia. 2011 Feb;13(2):81-97.

1H MRS of intramyocellular lipids in soleus muscle at 7 T: spectral simplification by using long echo times without water suppression.
Ren J, Sherry AD, Malloy CR, Magn Reson Med. 2010 Sep;64(3):662-71

Ultra-short echo time (UTE) MR imaging of the lung: comparison between normal and emphysematous lungs in mutant mice.
Takahashi M, Togao O, Obara M, van Cauteren M, Ohno Y, Doi S, Kuro-o M, Malloy C, Hsia CC, Dimitrov I, J Magn Reson Imaging. 2010 Aug;32(2):326-33.

Energetics and metabolism in the failing heart: important but poorly understood.
Turer AT, Malloy CR, Newgard CB, Podgoreanu MV, Curr Opin Clin Nutr Metab Care. 2010 Jul;13(4):458-65.

Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate.

Moreno KX, Sabelhaus SM, Merritt ME, Sherry AD, Malloy CR, Am J Physiol Heart Circ Physiol. 2010 May;298(5):H1556-64

Hyperpolarized 89Y complexes as pH sensitive NMR probes.
Jindal AK, Merritt ME, Suh EH, Malloy CR, Sherry AD, Kovács Z, J Am Chem Soc. 2010 Feb 17;132(6):1784-5.

Polymeric PARACEST MRI contrast agents as potential reporters for gene therapy.
Wu Y, Carney CE, Denton M, Hart E, Zhao P, Streblow DN, Sherry AD, Woods M, Org Biomol Chem. 2010 Dec 7;8(23):5333-8.

Measurement of N-acetylaspartylglutamate in the human frontal brain by 1H-MRS at 7 T.
Choi C, Ghose S, Uh J, Patel A, Dimitrov IE, Lu H, Douglas D, Ganji S, Magn Reson Med. 2010 Nov;64(5):1247-51

A responsive europium(III) chelate that provides a direct readout of pH by MRI.
Wu Y, Soesbe TC, Kiefer GE, Zhao P, Sherry AD, J Am Chem Soc. 2010 Oct 13;132(40):14002-3

The population of SAP and TSAP isomers in cyclen-based lanthanide(III) chelates is substantially affected by solvent.
Miller KJ, Saherwala AA, Webber BC, Wu Y, Sherry AD, Woods M, Inorg Chem. 2010 Oct 4;49(19):8662-4

In vitro evaluation of novel polymer-coated magnetic nanoparticles for controlled drug delivery
Rahimi M, Wadajkar A, Subramanian K, Yousef M, Cui W, Hsieh JT, Nguyen KT, Nanomedicine. 2010 Oct;6(5):672-80.

MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting.
De León-Rodríguez LM, Lubag A, Udugamasooriya DG, Proneth B, Brekken RA, Sun X, Kodadek T, Dean Sherry A, J Am Chem Soc. 2010 Sep 22;132(37):12829-31

Effect of pyruvate and HEPES on rat lung allograft acidosis and cell death after long-term hypothermic storage.
Peltz M, Milchgrub S, Jessen ME, Meyer DM, Transplant Proc. 2010 Sep;42(7):2771-6.

The retinoid signaling pathway inhibits hematopoiesis and uncouples from the Hox genes during hematopoietic development.
Szatmari I, Iacovino M, Kyba M, Stem Cells. 2010 Sep;28(9):1518-29

Multifunctional Polymeric Scaffolds for Enhancement of PARACEST Contrast Sensitivity and Performance: The Effects of Random Copolymer Variations.
Wu Y, Zhao P, Kiefer GE, Sherry AD, Macromolecules. 2010 Aug 24;43(16):6616-6624.

Imaging beta-galactosidase activity in human tumor xenografts and transgenic mice using a chemiluminescent substrate.
Liu L, Mason RP, PLoS One. 2010 Aug 6;5(8):e12024

Activation of a PARACEST agent for MRI through selective outersphere interactions with phosphate diesters.
Huang CH, Hammell J, Ratnakar SJ, Sherry AD, Morrow JR, Inorg Chem. 2010 Jul 5;49(13):5963-70.

S-Gal, a novel 1H MRI reporter for beta-galactosidase.
Cui W, Liu L, Kodibagkar VD, Mason RP, Magn Reson Med. 2010 Jul;64(1):65-71

Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet.
Sunny NE, Satapati S, Fu X, He T, Mehdibeigi R, Spring-Robinson C, Duarte J, Potthoff MJ, Browning JD, Burgess SC, Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1226-35

Assessment of renal fibrosis with diffusion-weighted MR imaging: study with murine model of unilateral ureteral obstruction.
Togao O, Doi S, Kuro-o M, Masaki T, Yorioka N, Takahashi M, Radiology. 2010 Jun;255(3):772-80.

Multimodality imaging of hypoxia in preclinical settings.
Mason RP, Zhao D, Pacheco-Torres J, Cui W, Kodibagkar VD, Gulaka PK, Hao G, Thorpe P, Hahn EW, Peschke P, Q J Nucl Med Mol Imaging. 2010 Jun;54(3):259-80.

Alternatives to gadolinium-based metal chelates for magnetic resonance imaging.
Viswanathan S, Kovacs Z, Green KN, Ratnakar SJ, Sherry AD, Chem Rev. 2010 May 12;110(5):2960-3018.

Improved synthesis of DOTA tetraamide ligands for lanthanide(III) ions: a tool for increasing the repertoire of potential PARACEST contrast agents for MRI and/or fluorescent sensors.
De León-Rodríguez LM1, Viswanathan S, Sherry AD, Contrast Media Mol Imaging. 2010 May-Jun;5(3):121-5

A concentration-independent method to measure exchange rates in PARACEST agents.
Dixon WT, Ren J, Lubag AJ, Ratnakar J, Vinogradov E, Hancu I, Lenkinski RE, Sherry AD, Magn Reson Med. 2010 Mar;63(3):625-32

Responsive MRI agents for sensing metabolism in vivo.
De Leon-Rodriguez LM, Lubag AJ, Malloy CR, Martinez GV, Gillies RJ, Sherry AD, Acc Chem Res. 2009 Jul 21;42(7):948-57

Evidence for reverse flux through pyruvate kinase in skeletal muscle.
Jin ES, Sherry AD, Malloy CR, Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E748-57.

Orientation of lipid strands in the extracellular compartment of muscle: effect on quantitation of intramyocellular lipids.
Khuu A, Ren J, Dimitrov I, Woessner D, Murdoch J, Sherry AD, Malloy CR, Magn Reson Med. 2009 Jan;61(1):16-21

Lanthanide(III) complexes of tris(amide) PCTA derivatives as potential bimodal magnetic resonance and optical imaging agents.
Rojas-Quijano FA, Benyó ET, Tircsó G, Kálmán FK, Baranyai Z, Aime S, Sherry AD, Kovács Z, Chemistry. 2009 Dec 7;15(47):13188-200.

Primer on gadolinium chemistry.
Sherry AD, Caravan P, Lenkinski RE, J Magn Reson Imaging. 2009 Dec;30(6):1240-8

Nanoassembled capsules as delivery vehicles for large payloads of high relaxivity Gd3+ agents.
Plush SE, Woods M, Zhou YF, Kadali SB, Wong MS, Sherry AD, J Am Chem Soc. 2009 Nov 4;131(43):15918-23

In vivo detection of serine in the human brain by proton magnetic resonance spectroscopy (1H-MRS) at 7 Tesla.
Choi C, Dimitrov I, Douglas D, Zhao C, Hawesa H, Ghose S, Tamminga CA, Magn Reson Med. 2009 Oct;62(4):1042-6.

Comparison of 1H blood oxygen level-dependent (BOLD) and 19F MRI to investigate tumor oxygenation.
Zhao D, Jiang L, Hahn EW, Mason RP, Magn Reson Med. 2009 Aug;62(2):357-64

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry.
Morrish F, Isern N, Sadilek M, Jeffrey M, Hockenbery DM, Oncogene. 2009 Jul 9;28(27):2485-91.

Modulation of water exchange in Eu(III) DOTA-tetraamide complexes: considerations for in vivo imaging of PARACEST agents.
Mani T, Tircsó G, Togao O, Zhao P, Soesbe TC, Takahashi M, Sherry AD, Contrast Media Mol Imaging. 2009 Jul-Aug;4(4):183-91.

Measurement of glutathione in human brain at 3T using an improved double quantum filter in vivo.
Choi C, Zhao C, Dimitrov I, Douglas D, Coupland NJ, Kalra S, Hawesa H, Davis J, J Magn Reson. 2009 Jun;198(2):160-6

(S)-5-(p-nitrobenzyl)-PCTA, a promising bifunctional ligand with advantageous metal ion complexation kinetics.
Tircsó G, Benyó ET, Suh EH, Jurek P, Kiefer GE, Sherry AD, Kovács Z, Bioconjug Chem. 2009 Mar 18;20(3):565-75.

Synthesis and evaluation of lanthanide ion DOTA-tetraamide complexes bearing peripheral hydroxyl groups.
Pasha A, Lin M, Tircsó G, Rostollan CL, Woods M, Kiefer GE, Sherry AD, Sun X, J Biol Inorg Chem. 2009 Mar;14(3):421-38

Multi-frequency PARACEST agents based on europium(III)-DOTA-tetraamide ligands.
Viswanathan S, Ratnakar SJ, Green KN, Kovacs Z, De León-Rodríguez LM, Sherry AD, Angew Chem Int Ed Engl. 2009;48(49):9330-3

Imaging the tissue distribution of glucose in livers using a PARACEST sensor.
Ren J, Trokowski R, Zhang S, Malloy CR, Sherry AD, Magn Reson Med. 2008 Nov;60(5):1047-55

Inhibition of carbohydrate oxidation during the first minute of reperfusion after brief ischemia: NMR detection of hyperpolarized 13CO2 and H13CO3-.
Merritt ME, Harrison C, Storey C, Sherry AD, Malloy CR,

Alterations in hepatic glucose and energy metabolism as a result of calorie and carbohydrate restriction.
Browning JD, Weis B, Davis J, Satapati S, Merritt M, Malloy CR, Burgess SC, Hepatology. 2008 Nov;48(5):1487-96.

Composition of adipose tissue and marrow fat in humans by 1H NMR at 7 Tesla.
Ren J, Dimitrov I, Sherry AD, Malloy CR, J Lipid Res. 2008 Sep;49(9):2055-62.

The effect of the amide substituent on the biodistribution and tolerance of lanthanide(III) DOTA-tetraamide derivatives.
Woods M, Caravan P, Geraldes CF, Greenfield MT, Kiefer GE, Lin M, McMillan K, Prata MI, Santos AC, Sun X, Wang J, Zhang S, Zhao P, Sherry AD, Invest Radiol. 2008 Dec;43(12):861-70.

Polymeric PARACEST agents for enhancing MRI contrast sensitivity.
Wu Y, Zhou Y, Ouari O, Woods M, Zhao P, Soesbe TC, Kiefer GE, Sherry AD, J Am Chem Soc. 2008 Oct 22;130(42):13854-5

Proton imaging of siloxanes to map tissue oxygenation levels (PISTOL): a tool for quantitative tissue oximetry.
Kodibagkar VD, Wang X, Pacheco-Torres J, Gulaka P, Mason RP, NMR Biomed. 2008 Oct;21(8):899-907

Partial resistance to peroxisome proliferator-activated receptor-alpha agonists in ZDF rats is associated with defective hepatic mitochondrial metabolism.
Satapati S, He T, Inagaki T, Potthoff M, Merritt ME, Esser V, Mangelsdorf DJ, Kliewer SA, Browning JD, Burgess SC, Diabetes. 2008 Aug;57(8):2012-21

Complicating factors in the application of the "average method" for determining the contribution of gluconeogenesis.
Burgess SC, Chandramouli V, Browning JD, Schumann WC, Previs SF, J Appl Physiol (1985). 2008 Jun;104(6):1852-3

The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain.
Hanaoka K, Lubag AJ, Castillo-Muzquiz A, Kodadek T, Sherry AD, Magn Reson Imaging. 2008 Jun;26(5):608-17

Pten haploinsufficiency accelerates formation of high-grade astrocytomas.
Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF, Cancer Res. 2008 May 1;68(9):3286-94.

Size-induced enhancement of chemical exchange saturation transfer (CEST) contrast in liposomes.
Zhao JM, Har-el YE, McMahon MT, Zhou J, Sherry AD, Sgouros G, Bulte JW, van Zijl PC, J Am Chem Soc. 2008 Apr 16;130(15):5178-84.

Labeling of adenovirus particles with PARACEST agents.
Vasalatiy O, Gerard RD, Zhao P, Sun X, Sherry AD, Bioconjug Chem. 2008 Mar;19(3):598-606

Towards the rational design of MRI contrast agents: electron spin relaxation is largely unaffected by the coordination geometry of gadolinium(III)-DOTA-type complexes.
Borel A, Bean JF, Clarkson RB, Helm L, Moriggi L, Sherry AD, Woods M, Chemistry. 2008;14(9):2658-67

Synthesis and relaxometric studies of a dendrimer-based pH-responsive MRI contrast agent.
Ali MM, Woods M, Caravan P, Opina AC, Spiller M, Fettinger JC, Sherry AD, Chemistry. 2008;14(24):7250-8

13C isotopomer analysis of glutamate by heteronuclear multiple quantum coherence-total correlation spectroscopy (HMQC-TOCSY).
Carvalho RA, Jeffrey FM, Sherry AD, Malloy CR, FEBS Lett. 1998 Dec 4;440(3):382-6.

13C NMR measurements of human gluconeogenic fluxes after ingestion of [U-13C]propionate, phenylacetate, and acetaminophen.
Jones JG, Solomon MA, Sherry AD, Jeffrey FM, Malloy CR, Am J Physiol. 1998 Nov;275(5 Pt 1):E843-52.

Quantitation of intracellular [Na+] in vivo by using TmDOTP5- as an NMR shift reagent and extracellular marker.
Winter PM, Seshan V, Makos JD, Sherry AD, Malloy CR, Bansal N, J Appl Physiol (1985). 1998 Nov;85(5):1806-12.

Distribution of TmDOTP5- in rat tissues: TmDOTP5- vs. CoEDTA- as markers of extracellular tissue space.
Makos JD, Malloy CR, Sherry AD, J Appl Physiol (1985). 1998 Nov;85(5):1800-5.

39K NMR measurement of intracellular potassium during ischemia in the perfused guinea pig heart.
Radford NB, Babcock EE, Richman A, Szczepaniak L, Malloy CR, Sherry AD, Magn Reson Med. 1998 Oct;40(4):544-50.

Measurement of hepatic glucose output, krebs cycle, and gluconeogenic fluxes by NMR analysis of a single plasma glucose sample.
Jones JG, Carvalho RA, Franco B, Sherry AD, Malloy CR, Anal Biochem. 1998 Oct 1;263(1):39-45.

Dissociation of intracellular sodium from contractile state in guinea-pig hearts treated with ouabain.
Radford NB, Makos JD, Ramasamy R, Sherry AD, Malloy CR, J Mol Cell Cardiol. 1998 Mar;30(3):639-47.

Right-shifting the oxyhemoglobin dissociation curve with RSR13: effects on high-energy phosphates and myocardial recovery after low-flow ischemia.
Woods JA, Storey CJ, Babcock EE, Malloy CR, J Cardiovasc Pharmacol. 1998 Mar;31(3):359-63

Effects of dichloroacetate on mechanical recovery and oxidation of physiologic substrates after ischemia and reperfusion in the isolated heart.
Barak C, Reed MK, Maniscalco SP, Sherry AD, Malloy CR, Jessen ME, J Cardiovasc Pharmacol. 1998 Mar;31(3):336-44.

Effects of aminooxyacetate on glutamate compartmentation and TCA cycle kinetics in rat hearts.
Sherry AD, Zhao P, Wiethoff AJ, Jeffrey FM, Malloy CR, Am J Physiol. 1998 Feb;274(2 Pt 2):H591-9.

Determination of the intracellular sodium concentration in perfused mouse liver by 31P and 23Na magnetic resonance spectroscopy.
Colet JM, Makos JD, Malloy CR, Sherry AD, Magn Reson Med. 1998 Jan;39(1):155-9.

Effects of glutamate and aspartate on myocardial substrate oxidation during potassium arrest.
Reed MK, Barak C, Malloy CR, Maniscalco SP, Jessen ME, J Thorac Cardiovasc Surg. 1996 Dec;112(6):1651-60.

Isotopic methods for probing organization of cellular metabolism.
Sherry AD, Malloy CR, Cell Biochem Funct. 1996 Dec;14(4):259-68.

13C isotopomer model for estimation of anaplerotic substrate oxidation via acetyl-CoA.
Jeffrey FM, Storey CJ, Sherry AD, Malloy CR, Am J Physiol. 1996 Oct;271(4 Pt 1):E788-99.

Effects of ischemia on intracellular sodium and phosphates in the in vivo rat liver.
Xia ZF, Horton JW, Zhao PY, Babcock EE, Sherry AD, Malloy CR, J Appl Physiol (1985). 1996 Sep;81(3):1395-403.

Oxidation of acetate in rabbit skeletal muscle: detection by 13C NMR spectroscopy in vivo.
Szczepaniak L, Babcock EE, Malloy CR, Sherry AD, Magn Reson Med. 1996 Sep;36(3):451-7.

Substrate selection early after reperfusion of ischemic regions in the working rabbit heart.
Solomon MA, Jeffrey FM, Storey CJ, Sherry AD, Malloy CR, Magn Reson Med. 1996 Jun;35(6):820-6.

Cardioprotective effects of 70-kDa heat shock protein in transgenic mice.
Radford NB, Fina M, Benjamin IJ, Moreadith RW, Graves KH, Zhao P, Gavva S, Wiethoff A, Sherry AD, Malloy CR, Williams RS, Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2339-42.

Contribution of various substrates to total citric acid cycle flux and anaplerosis as determined by 13C isotopomer analysis and O2 consumption in the heart.
Malloy CR, Jones JG, Jeffrey FM, Jessen ME, Sherry AD, MAGMA. 1996 Mar;4(1):35-46.

Effects of different oxidative insults on intermediary metabolism in isolated perfused rat hearts.
Jones JG, Le TH, Storey CJ, Sherry AD, Malloy CR, Burton KP, Free Radic Biol Med. 1996;20(4):515-23.

A 13C isotopomer n.m.r. method for monitoring incomplete beta-oxidation of fatty acids in intact tissue.
Gavva SR, Wiethoff AJ, Zhao P, Malloy CR, Sherry AD, Biochem J. 1994 Nov 1;303 ( Pt 3):847-53.

Effect of metoprolol on myocardial function and energetics in patients with nonischemic dilated cardiomyopathy: a randomized, double-blind, placebo-controlled study.
Eichhorn EJ, Heesch CM, Barnett JH, Alvarez LG, Fass SM, Grayburn PA, Hatfield BA, Marcoux LG, Malloy CR, J Am Coll Cardiol. 1994 Nov 1;24(5):1310-20.

Effects of oxidant exposure on substrate utilization and high-energy phosphates in isolated rat hearts.
Burton KP, Jones JG, Le TH, Sherry AD, Malloy CR, Circ Res. 1994 Jul;75(1):97-104.

Orientation-conserved transfer of symmetric Krebs cycle intermediates in mammalian tissue.
Sherry AD, Sumegi B, Miller B, Cottam GL, Gavva S, Jones JG, Malloy CR, Biochemistry. 1994 May 24;33(20):6268-75.

13C isotopomer analyses in intact tissue using [13C]homonuclear decoupling.
Sherry AD, Zhao P, Wiethoff A, Malloy CR, Magn Reson Med. 1994 Apr;31(4):374-9.

In vivo studies of cellular energy state, pH, and sodium in rat liver after thermal injury.
Xia ZF, Horton JW, Zhao PY, Bansal N, Babcock EE, Sherry AD, Malloy CR, J Appl Physiol (1985). 1994 Apr;76(4):1507-11.

A method for obtaining 13C isotopomer populations in 13C-enriched glucose.
Jones JG, Cottam GL, Miller BC, Sherry AD, Malloy CR, Anal Biochem. 1994 Feb 15;217(1):148-52.

Lipoamide influences substrate selection in post-ischaemic perfused rat hearts.
Sumegi B, Butwell NB, Malloy CR, Sherry AD, Biochem J. 1994 Jan 1;297 ( Pt 1):109-13.